Ovarian Cancer
Ovarian cancer starts in the cell tissues of the ovaries. Ovaries are a pair of organs from the feminine reproductive system. Similar to egg bags, ovaries release one egg every month. Most ovarian cancers are either epithelial carcinomas (begin in the cells of the ovary’s surface) or malignant germ cell tumours (begin in cells of the eggs).
Although ovarian cancer is the seventh most diagnosed type of cancer in Canadian women, it is the fifth most important cause of cancer-attributed deaths amongst Canadian women. The relative 5-year survival rate for ovarian cancer in Canada is estimated at 42%.
It has been estimated that for the year 2011, 2,600 new ovarian cancer diagnoses would be made in Canada and 1,750 Canadian women would die from the disease. Based on recent statistics, one in 69 Canadian women is expected to develop ovarian cancer during her lifetime; one in 92 women will die of the disease.
This section is still in construction. Please come back shortly for a more complete description of the disease.
Research projects focused on this topic
- Regulation of ribosome biogenesis by Pygopus in epithelial ovarian cancer
- Identifying signal transduction pathways regulated by malignant ascites
- Deletion analysis of BRCA1 and BRCA2 loci in high risk breast and/or ovarian cancer families of French Canadian descent
- The Role of Butyrophilin in the Immunomodulation of Ovarian Cancer Microenvironment
- Assessment of novel markers with potential prognostic significance in ovarian cancer
- Evaluating the contribution of BRCA1 and BRCA2 in French Canadian ovarian cancers cases
- A novel ubiquitin signaling pathway in the regulation of BRCA1 (Breast Cancer 1, early onset) tumor suppressor function
- Characterization of the hypomethylation status of the RUNX1 and RUNX2 genes in advanced ovarian cancer: possible role of RUNX1 and RUNX2 in ovarian cancer progression, invasion/metastasis and chemoresistance









