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Current research projects

Year after year, the most promising research projects across Canada are selected by our expert panels for Cancer Research Society (CRS) funding. The following table lists all of our projects currently being funded.

For the project description or details on the associated program, click on the following links.

Researcher's name Research center Project's name Program
El Bachir Affar Maisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec A novel ubiquitin signaling pathway in the regulation of BRCA1 (Breast Cancer 1, early onset) tumor suppressor function Operating Grants (Basic Research)
Jacques Archambault Institut de recherches cliniques de Montréal, Quebec Small molecule inhibitors of HPV E6-mediated degradation of P53 Operating Grants (Basic Research)
Kristan Aronson Queen's University Cancer Research Institute, Kingston, Ontario Measuring Traffic Exposure and Assessing Environmental Equity Operating Grants (environment-cancer)
Rebecca Auer Ottawa Hospital Research Institute, Ontario The Role of Tissue Factor Following Surgery in the Development of Postoperative Metastatic Disease Operating Grants (Basic Research)
Dimcho Bachvarov Centre de recherche du CHUQ, Hôtel-Dieu de Québec, Quebec Characterization of the hypomethylation status of the RUNX1 and RUNX2 genes in advanced ovarian cancer: possible role of RUNX1 and RUNX2 in ovarian cancer progression, invasion/metastasis and chemoresistance Operating Grants (Basic Research)
Nicole Beauchemin The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec Genetic control of susceptibility to colon cancer development Operating Grants (Basic Research)
Yohan Bossé Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Quebec Gene-smoking interaction in lung cancer Operating Grants (environment-cancer)
Maxime Bouchard The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec Gata3 and the Androgen Receptor Response in Prostate Cancer Operating Grants (Basic Research)
Julie Brill The Hospital for Sick Children, Toronto, Ontario Identifying the PI 4-kinases that drive oncogenic GOLPH3 signaling in Drosophila Operating Grants (Basic Research)
Robert Bruce University of Toronto, Ontario Dietary risk factors for colorectal cancer Operating Grants (environment-cancer)
Jean-François Cailhier Université de Montréal, Institut du cancer de Montéal, Quebec The Role of Butyrophilin in the Immunomodulation of Ovarian Cancer Microenvironment Operating Grants (Basic Research)
Hong Chang University Health Network, Toronto, Ontario Identification of novel biomarker in multiple myeloma therapy resistance Operating Grants (Basic Research)
Frederic Charron Institut de recherches cliniques de Montréal, Quebec The detection and identification of medulloblastoma Operating Grants (Basic Research)
Mario Chevrette Research Institute of the McGill University Health Centre, Montreal, Quebec Identification of the natural regulator of telomerase: possible role in controlling telomerase expression in cancer cells Operating Grants (Basic Research)
Jocelyn Côté University of Ottawa, Ontario The Role of PRMT1 Alternatively Spliced Isoform v2 in Breast Cancer Pathogenesis Operating Grants (Basic Research)
Damien D'Amours Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Roles of cancer-associated kinases in cell cycle progression Operating Grants (Basic Research)
Javier M. Di Noia Institut de recherches cliniques de Montréal, Quebec Regulation of the mutagenic capacity of the antibody diversification enzyme AID by Hsp90 Operating Grants (Basic Research)
François Dragon Université du Québec à Montréal (UQAM), Quebec Regulation of ribosome biogenesis in cancer cells Operating Grants (Basic Research)
Régen Drouin Université de Sherbrooke, Quebec Nuclear telomere architecture as biomarker in glioblastomas Operating Grants (Basic Research)
Trevor Dummer Dalhousie University, Halifax, Nova Scotia Cancer risk and outdoor air pollution in Halifax Regional Muncipality, Nova Scotia Operating Grants (environment-cancer)
Sean Egan The Hospital for Sick Children, Toronto, Ontario Notch4 as potential target in breast cancer stem cells Operating Grants (Basic Research)
Gregory Emery Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Endocytic regulation of Notch signaling Operating Grants (Basic Research)
Urban Emmenegger Sunnybrook Research Institute, University of Toronto, Ontario Studying autophagy as a complemetary therapeutic target in antivascular tumor therapy Operating Grants (Basic Research)
François Fagotto McGill University, Montreal, Quebec Activation of beta-catenin in Wnt signaling Operating Grants (Basic Research)
William Foulkes Research Institute of the McGill University Health Centre, Montreal, Quebec Assessing the contribution of spindle assembly checkpoint genes to colorectal neoplasia Operating Grants (Basic Research)
William Foulkes Lady Davis Institute, McGill University, Montreal, Quebec A multimodal genomic analysis strategy to identify novel breast cancer genes Operating Grants (Basic Research)
Luc Gaudreau Université de Sherbrooke, Quebec Characterization of estrogen-mediated repression of dioxin receptor signaling Operating Grants (environment-cancer)
Abhijit Guha University of Toronto, Ontario Aberrations in EGFR in Human GBMs: Novel Diagnostic and Biomarker Strategies Operating Grants (Basic Research)
Chantal Guillemette Centre de recherche du CHUQ, Hôtel-Dieu de Québec, Quebec Prognostic markers of prostate cancer recurrence after prostatectomy Operating Grants (Basic Research)
Martin Guimond Maisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec The effect of GVHD on the peripheral niche regulating lymphocyte homeostasis Operating Grants (Basic Research)
Razq Hakem University Health Network, Toronto, Ontario Analysis of the cooperation of p53 with RNF8 and RNF168 in suppressing genomic instability and cancer Operating Grants (Basic Research)
John Hassell McMaster University, Hamilton, Ontario Identification and characterization of agents that enhance sensitivity to chemotherapy Operating Grants (Basic Research)
Mitsuhiko Ikura University Health Network / Ontario Cancer Institute, Toronto, Ontario Structural mechanisms of the Lfc oncogene regulation Operating Grants (Basic Research)
Mitsuhiko Ikura University Health Network / Ontario Cancer Institute, Toronto, Ontario Structural investigation on Ras Signaling and regulatory mechanisms Operating Grants (Basic Research)
Subburaj Ilangumaran Université de Sherbrooke, Quebec Regulation of Met signaling by Socs1 in hepatocellular carcinoma Operating Grants (Basic Research)
Suzanne Kamel-Reid University Health Network / Ontario Cancer Institute, Toronto, Ontario New prognostic markers in mantle cell lymphoma Operating Grants (Basic Research)
Svetlana Komarova McGill University, Montreal, Quebec Link between osteolysis and pain during breast cancer metastases to bone Operating Grants (Basic Research)
Jean-Claude Labbé Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Regulation of PAR-6 levels during cell polarity establishment and maintenance Operating Grants (Basic Research)
Benjamin Lacroix Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Quantitative Analysis of Cytokinesis in situ
Hugo Lavoie Université de Montréal, Quebec Specific modulation of Ras-MAPK signalling by a mRNA-binding complex
Michel Lebel Laval University Cancer Research Center, Quebec, Quebec Identification of molecules that will inhibit chemoresistance conferred by YB-1 in breast tumors Operating Grants (Basic Research)
Jonathan M. Lee University of Ottawa, Ontario The good oncogene: eEF1A2 and the control of breast cancer outcome Operating Grants (Basic Research)
Megan K. Levings University of British Columbia, Vancouver, British Columbia Regulatory T cell therapy for graft versus host disease Operating Grants (Basic Research)
Shun-Cheng (Shawn) Li University of Western Ontario, London, Ontario Exploring the Cten-DLC1 signaling axis for cancer intervention Operating Grants (Basic Research)
Gang Li University of British Columbia, Vancouver, British Columbia Mechanisms of anti-angiogenic role of ING4 in human melanoma Operating Grants (Basic Research)
David Litchfield University of Western Ontario, London, Ontario Rational Design of Novel Molecular-Targeted Inhibitors of Cancer Cell Proliferation Operating Grants (Basic Research)
Sylvie Mader Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Mechanisms of action of full antiestrogens in breast cancer cells Operating Grants (Basic Research)
Sylvie Mader Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Role of retinoic acid synthesis in mammary gland development and tumorigenesis Operating Grants (Basic Research)
Marco Marra BC Cancer Agency, Vancouver, British Columbia Characterizing cell-based models for non-Hodgkin's lymphoma Operating Grants (Basic Research)
Alberto Martin University of Toronto, Ontario Delineating the role of the mismatch repair pathway in suppressing colon carcinogenesis Operating Grants (Basic Research)
John McLaughlin Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario Advanced spatial analyses to characterize environmental impacts on cancer risk: Phase 1 Operating Grants (environment-cancer)
Susan Meakin University of Western Ontario, London, Ontario Mechanisms of Trk-Dependent Cell Death in Human Brain Tumors Operating Grants (Basic Research)
Sylvain Meloche Université de Montréal, IRIC, Quebec Role of MEK-ERK1/2 signaling in the initiation, genetic instability and maintenance of colorectal cancer Operating Grants (Basic Research)
Tarik Moroy Institut de recherches cliniques de Montréal, Quebec Role of the transcription factor Gfi1 and the Gfi136N variant in Acute myeloid leukemia (AML) Operating Grants (Basic Research)
Karen Mossman McMaster University Health & Science Center, Hamilton, Ontario Characterization of BHV-1 as a potent oncolytic virus for the treatment of multiple cancer types Operating Grants (Basic Research)
William J. Muller The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec Role of Akt family signaling in ErbB2 mammary tumour progression Operating Grants (Basic Research)
Ivan Robert Nabi University of British Columbia, Vancouver, British Columbia Autocrine motility factor as a targeted delivery agent for breast cancer treatment Operating Grants (Basic Research)
Ivan Robert Nabi University of British Columbia, Vancouver, British Columbia Molecular Characterization of the Pseudopodia of Metastatic Tumor Cells Operating Grants (Basic Research)
Michael Ohh University of Toronto, Ontario Role of Cbl in Juvenile Myelomonocytic Leukemia Operating Grants (Basic Research)
Marie-Élise Parent INRS-Institut Armand-Frappier, Université de Montréal, Quebec Quebec Research Program for Prostate Cancer Prevention GRePEC
Arnim Pause The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec Metabolic role of the tumor suppressor gene HD-PTP in lung tumorigenesis Operating Grants (Basic Research)
Christian Rocheleau McGill University, Montreal, Quebec Analysis of new negative regulators/candidate tumor suppressors in EGFR/Ras/MAPK signaling Operating Grants (Basic Research)
Francis Rodier Université de Montréal, Institut du cancer de Montéal, Quebec Molecular detection of lymph node metastasis in uterine cervical carcinoma Operating Grants (Basic Research)
Kirill Rosen Dalhousie University, Halifax, Nova-Scotia Beta-catenin as a mediator of three-dimensional tumor growth Operating Grants (Basic Research)
Philippe Roux Institute for Research in Immunology and Cancer, Université de Montréal, Quebec Regulation and Function of the RSK Family in Breast Cancer Operating Grants (Basic Research)
Isabelle Royal Research Centre of the University of Montreal Hospital Centre, Quebec Function and regulation of the protein tyrosine phosphatase DEP-1 in angiogenesis and tumor progression Operating Grants (Basic Research)
Luc Sabourin Ottawa Hospital Research Institute, Ontario The role of Periostin/OSF-2 in ErbB2-driven tumorigenesis Operating Grants (Basic Research)
Philippe Sarret Centre Hospitalier de l'Université de Sherbrooke, Quebec Role of neurotensin receptor in cancer chronic pain Operating Grants (Basic Research)
Hervé Sartelet Sainte-Justine University Hospital Centre, Université de Montréal, Quebec Regulation of the pro-invasive properties of neuroblastoma-initiating cells by membrane-type 1 matrix metalloproteinase Operating Grants (Basic Research)
Peter Siegel The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec Defining Mechanisms by which CCN3 Promotes the Formation of Osteolytic Bone Metastases Operating Grants (Basic Research)
Jack Siemiatycki Centre de recherche du CHUM (CRCHUM), Montreal, Quebec Determining the cancer risks associated with different aspects of our environment The Guzzo Environment-Cancer Research Chair of the Cancer Research Society in partnership with the Université de Montréal
Nahum Sonenberg The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec mTOR inhibition and translation control of pancreatic neuroendocrine tumours CRS / CNETS Grant
John Stagg Research Centre of the University of Montreal Hospital Centre, Quebec CD73-mediated chemoresistance in triple negative breast cancer Operating Grants (Basic Research)
Yves St-Pierre Institut national de la recherche scientifique (INRS), Laval, Quebec Functional relationship between EGR-1 and MMP-9 during lymphoma progression Operating Grants (Basic Research)
Bernard Têtu Centre de recherche du CHUQ, Hôtel-Dieu de Québec, Quebec Assessment of novel markers with potential prognostic significance in ovarian cancer Operating Grants (Basic Research)
Jacques Thibodeau Université de Montréal, Quebec Targeting of tumor vaccine antigens to MHC II by-products and chaperones expressed on antigen-presenting cells Operating Grants (Basic Research)
Patricia Tonin Montreal General Hospital, Quebec Evaluating the contribution of BRCA1 and BRCA2 in French Canadian ovarian cancers cases Operating Grants (Basic Research)
Joe Torchia University of Western Ontario, London, Ontario The role of TGF-beta signalling in epigenetic stability Operating Grants (Basic Research)
Michel L. Tremblay McGill University, Montreal, Quebec Linking cancer anorexia-cachexia syndrome, resting energy expenditure and chronic inflammation state in patients with pancreatic cancer through cellular metabolic mechanisms and their unique metastatic control CRS / Rob Lutterman Pancreatic Cancer Research Grant
Mathieu Tremblay The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec Role of GATA3 factor in prostate cancer
Valerie Wallace Ottawa Hospital Research Institute, Ontario Hedgehog target genes and medulloblastoma proliferation Operating Grants (Basic Research)
Rachel Wevrick University of Alberta, Edmonton, Alberta A cell model for MAGE over-expression in cancer progression and chemotherapy resistance Operating Grants (Basic Research)
John H. White McGill University, Montreal, Quebec Functional interactions of the vitamin D receptor with Class III histone deacetylase Sirtuin 1 Operating Grants (environment-cancer)
Nicole White St Michael's Hospital, Toronto, Ontario Identifying novel biomarkers for renal cell carcinoma through quantitative proteomic analysis: Moving into an era of personalized medicine
Sarah K. Wootton University of Guelph, Ontario Akt isoforms in lung tumorigenesis and identification of novel therapeutic targets CRS / Marjolaine-Bazinet Lung Cancer Research Grant
Jian Hui Wu Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec Development of bifunctional antiandrogens that suppress oncogenic activation of the androgen Operating Grants (Basic Research)
Ju Yan Université de Sherbrooke, Quebec Investigation of a new clonal event: Chromosome-arm-specific telomere elongation in acute lymphoblastic leukemia (ALL) Operating Grants (Basic Research)
Herman Yeger The Hospital for Sick Children, Toronto, Ontario The Role of Hypoxia/Hypercapnia Chemosensing in the Pathophysiology and Malignant Transformation of Carcinoids CRS / CNETS Grant
Maria Zannis-Hadjopoulos The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec The role of Ku protein in breast tumorigenesis: implications for therapy Operating Grants (Basic Research)
Xu-Dong Zhu McMaster University, Hamilton, Ontario Molecular Characterization of the Role of CSB in Tumorigenesis Operating Grants (Basic Research)