Past research projects (2009-2011)
|
Researcher |
Research centre |
Project name |
Focus of research |
|
Hôpital Maisonneuve-Rosemont, Montreal, Quebec |
The role of ubiquitination in the regulation of BRCA1 tumour suppressor function |
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|
Oliver Bathe |
University of Calgary, Alberta |
The influence of macrophages on the immunosuppressive tumour microenvironment |
Pancreatic cancer, Immunotherapy |
|
McGill University, Montreal, Quebec |
Role of GATA3 in prostate cancer |
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|
Antonio Conconi |
Centre hospitalier de l'Université de Sherbrooke, Quebec |
The fate of RNA polymerases during transcription-coupled nucleotide excision repair |
Multiple cancers |
|
Benoit Coulombe |
Institut de recherches cliniques de Montréal, Quebec |
Regulation of nuclear RNA polymerase biogenesis in TOR signaling |
Multiple cancers |
|
Fred Dick |
University of Western Ontario, London, Ontario |
The role of the retinoblastoma protein in TGF-beta induced growth arrest |
|
|
Institut de recherches cliniques de Montréal, Quebec |
Regulation of the mutagenic capacity of the antibody diversification enzyme AID by Hsp90 |
Multiple cancers |
|
|
Michael Gold |
University of British Columbia, Vancouver, British Columbia |
The role of leukocytes and inflammation in enhancing tumour metastasis |
|
|
Reginald Gorczynski |
University of Toronto, Ontario |
A shed soluble form of CD200 has prognostic and therapeutic implications in CLL |
|
|
Darel J. Hunting |
Centre hospitalier de l'Université de Sherbrooke, Quebec |
Development of sequence-targeted radiosensitizers |
Radiotherapy |
|
University Health Network, Toronto, Ontario |
NMR investigation on Ras signaling and regulatory mechanisms |
Multiple cancers |
|
|
Lucie Jeannotte |
Centre de recherche de l'Hôtel-Dieu de Québec, Quebec |
Biological impact of the loss of Hoxa5 function in mammary gland development and tumorigenesis |
|
|
Xiaoyan Jiang |
British Columbia Cancer Agency, Vancouver, British Columbia |
Overcoming Imatinib resistance in CML with combination therapy of new ABL and ILK inhibitors |
|
|
Maja Krajinovic |
CHU Sainte-Justine Research Center, Montreal, Quebec |
Preclinical validation of ALL relapse predisposing variants in DHFR and TS genes |
Leukemia, Children and young adult cancers |
|
Jean-Yves Masson |
Centre de recherche de l'Hôtel-Dieu de Québec, Quebec |
Targeting RAD51/PALB2/BRCA2 homologous recombination proteins as an anti-cancer approach |
|
|
Peter John McPherson |
University of Toronto, Ontario |
Interplay of pathways in the DNA damage response to interstrand crosslinks |
Multiple cancers |
|
Institut de recherches cliniques de Montréal, Quebec |
Role of the myeloid transcription factor Gfi1 and the Gfi136N variant in human acute myeloid leukemia |
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|
Michael Mowat |
University of Manitoba, Winnipeg, Manitoba |
Conditional knockout mouse models of the Deleted in liver cancer (Dlc) tumour suppressor genes |
|
|
University of British Columbia, Vancouver, British Columbia |
Molecular characterization of the pseudopodia of metastatic tumour cells |
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|
Christopher John Ong |
University of British Columbia, Vancouver, British Columbia |
SEMA3C as a novel target for treatment of advanced prostate cancer |
|
|
Arnim Pause |
McGill University, Montreal, Quebec |
Role of the inactive tyrosine phosphatase HD-PTP in lung cancer |
|
|
Laurence Pelletier |
Mount Sinai Hospital, Toronto, Ontario |
A genome-wide RNAi screen to identify regulators of cilia assembly in mammalian cells |
Multiple cancers |
|
Guy G. Poirier |
Centre hospitalier de l'Université Laval (CHUL), Quebec, Quebec |
Role of PARP-3 in epigenetic transcriptional regulation in neuroblastoma |
Brain & Nervous system tumours, Children and young adult cancers |
|
Lynne-Marie Postovit |
University of Western Ontario, London, Ontario |
Role of nodal in breast cancer metastasis |
|
|
Daniel Sinnett |
CHU Sainte-Justine Research Center, Montreal, Quebec |
Characterization of ETV6 gene targets |
Leukemia, Children and young adult cancers |
|
Robert Sladek |
McGill University, Montreal, Quebec |
Identification of gene networks mediating cancer cachexia |
Multiple cancers |
|
Xiaolong Yang |
Queen's University, Kingston, Ontario |
Identification and characterization of novel LATS kinase substrates |
Multiple cancers |
|
Jinyi Zhang |
Mount Sinai Hospital, Toronto, Ontario |
Role of a cytoskeletal regulatory protein in myelodysplastic syndrome |
